Entrepreneurial activities in rural areas in spite of existence of appropriate and varied situation have not been institutionalized yet. It is argued that varied restrictions and barriers forced entrepreneurs to leave the rural areas. This paper aims to investigate the most important barriers regarding entrepreneurial activities in rural areas of Zanjan. From purpose stand point the research method has applied nature. It is followed by field work as well as descriptive-analytical method. The statistical society composed of rural households of Ghani Baglo district. According to ١٣٩٠ census it is associated with ٣٣ villages, ٢٣٣٠ households and population of ٩٨٤٣. ١٩٥ households out of ١٢ villages were drawn. Data gathering technique is based on documentary as well as questionnaire. Data analysis is supported by principle component analysis. This study suggests that economic, individual, structural factors are capable of explaining ١٣.٦٤ % of the variations and are considered as the most prominent barriers regarding rural entrepreneurial activities. However, low place adherence, lack of job opportunities, insufficient capital, low job risk and change in jobs are among other rural entrepreneurial restrictions.